Sibutramine (usually as hydrochloride salt monohydrate) is an oral anorexiant. By 2010 it was marketed and prescribed as a supplement in the treatment of exogenous obesity with diet and exercise. It has been associated with increased cardiovascular events and stroke and withdrawn from the market in various countries and regions such as Australia, Canada, China, the European Union (EU), Hong Kong, India, Mexico, New Zealand, Philippines, Thailand And the United States.
Sibutramine is a reuptake inhibitor of serotonin norepinephrine (SNRI) structurally with amphetamine central action, although its mechanism of action differs.
Sibutramine was originally developed in 1988 by Boots in Nottingham, UK and marketed by Knoll Pharmaceuticals after BASF / Knoll AG's Boots Research Division in 1995 and recently was manufactured and marketed by Abbott Laboratories before its withdrawal from the market. It has been sold under a variety of brand names such as Reductil, Meridia, Siredia and Sibutrex. It is classified as a controlled substance in Annex IV in the United States.
Despite Sibutramine was banned in 2010 it is still widely used as a hidden active agent in several slimming supplements or slimming products. The following list, contains products which are containing it:
Lishou Slimming Pills
Lishou Slimming Coffee
The list will be continued.